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    • WHO records largest single-day increase in COVID-19 cases

    The World Health Organization (WHO) on Sunday reported more than 183,000 new coronavirus cases globally in the last 24 hours.

    The number is the largest single-day increase in coronavirus cases by count, according to The Associated Press.

    The most new cases were recorded in the Americas, making up 116,041 of the new cases, according to the WHO report.

    Overall, WHO reported a total of 8,708,008 confirmed COVID-19 cases and 461,715 deaths globally.

    The increase comes as many countries have started lifting restrictions put in place to mitigate the spread of the coronavirus.

    In the U.S., state officials have started lifting coronavirus restrictions to various degrees — in some cases leading to spikes.

    WHO reported 36,617 new cases in the U.S. and 690 new deaths, bringing the total number of cases to more than 2.2 million and total deaths to 118,895.

    The most new cases were reported in Brazil, with 54,771 new coronavirus cases, bringing the nation’s total to 1,032,913.:
    • Early update.

    Coronavirus Cases: 9,060,969

    Deaths: 470,940

    Underreported US death count: 122,248

    Originally posted by Boon Mee View Post
    it's been blown way out of proportion.
    Keep your friends close and your enemies closer


      • mRNA vaccine against Covid-19 shows initial success on monkeys

      Thailand seems to be moving closer to finding a Covid-19 vaccine after the first trial on monkeys proved to be successful, leaving them strong and immune to the virus. Scientists were scheduled to launch a second round of testing the mRNA vaccine on the animals on Monday (June 22).

      This success means the vaccine should be ready for human testing by October, Higher Education, Science, Research and Innovation Minister Suvit Maesincee said.

      After two weeks, researchers will check the vaccinated monkeys’ blood to see if they are still immune to Covid-19, before injecting a third dose in August.

      The vaccine is being tested on 13 monkeys, who are divided into three groups:

      • The first group of five received high doses of the vaccine, and four of the monkeys built up an immunity against the virus;
      • The second group of five monkeys were low doses of the virus, and four were able to create antibodies;
      • The remaining three monkeys were not vaccinated and were found to not be immune to the virus.

      Results of the second round of vaccination should be available at the end of July.:
      • Thai trials of Covid-19 vaccine reach make-or-break stage

      Thai scientists administered a second dose of an experimental Covid-19 vaccine to monkeys on Monday, looking for another positive response to enable clinical trials in humans as early as October.

      The Thai vaccine is one of at least 100 being worked on globally as the world reels from a devastating virus that has infected more than 8.7 million and killed 461,000, with Sunday's 183,000 cases the highest reported in a single day.

      Thirteen monkeys were immunised on Monday and the next two weeks will be critical in determining whether researchers can proceed with further tests.

      "We're going to analyse the immune response once again. If the immune response is very, very high, then this is a good one," said Kiat Ruxrungtham, director of Chulalongkorn University’s Centre of Excellence in Vaccine Research and Development.

      The government is backing the trials and hopes it can have a cost-effective vaccine manufactured domestically and ready for next year.

      The monkeys are divided into three groups, with one getting a high dose, another a low dose and the last none. They are receiving three injections in total, each a month apart.

      The first dose on May 23 prompted positive responses from all but one animal in the high-dose group and from three in the low-dose group, an outcome Dr Kiat called "very impressive".

      If there is a similar response after the second dose, Dr Kiat said, the programme would order 10,000 doses made for a human trial, adding that his group had been flooded with offers from volunteers.

      "The earliest we can get may be late September," he said of the doses. "But we don't expect it that soon, and the latest may be by November.":
      • Today’s update.

      Coronavirus Cases: 9,143,571

      Deaths: 472,541

      World population: 7,800,000,000 projection: 403,105,066 deaths

      Underreported US death count: 122,557

      Originally posted by Boon Mee View Post
      it's been blown way out of proportion.
      Keep your friends close and your enemies closer


        • How Covid-19 can damage the brain

        Some scientists suspect that Covid-19 causes respiratory failure and death not through damage to the lungs, but the brain – and other symptoms include headaches, strokes and seizures.

        For Julie Helms, it started with a handful of patients admitted to her intensive care unit at Strasbourg University Hospital in northeast France in early March 2020. Within days, every single patient in the ICU had Covid-19 – and it was not just their breathing difficulties that alarmed her.

        “They were extremely agitated, and many had neurological problems – mainly confusion and delirium,” she says. “We are used to having some patients in the ICU who are agitated and require sedation, but this was completely abnormal. It has been very scary, especially because many of the people we treated were very young – many in their 30s and 40s, even an 18-year-old.”

        Helms and her colleagues published a small study in the New England Journal of Medicine documenting the neurological symptoms in their Covid-19 patients, ranging from cognitive difficulties to confusion. All are signs of “encephalopathy” (the general term for damage to the brain) – a trend that researchers in Wuhan had noticed in coronavirus patients there in February.

        Now, more than 300 studies from around the world have found a prevalence of neurological abnormalities in Covid-19 patients, including mild symptoms like headaches, loss of smell (anosmia) and tingling sensations (arcoparasthesia), up to more severe outcomes such as aphasia (inability to speak), strokes and seizures. This is in addition to recent findings that the virus, which has been largely considered to be a respiratory disease, can also wreak havoc on the kidneys, liver, heart, and just about every organ system in the body.

        “We don’t know yet if the encephalopathy is more severe with Covid-19 than with other viruses, but I can tell you we’ve been seeing quite a lot of it,” says neurologist Elissa Fory of the Henry Ford Foundation in Detroit, Michigan. “As the number of cases increases, you will start to see not only the common manifestations but also the uncommon manifestations – and we’re seeing them all at once, which is not something any of us have encountered in our lifetimes.”

        Estimates of exact prevalence vary, but it seems that roughly 50% of patients diagnosed with Sars-CoV-2 – the virus responsible for causing the illness Covid-19 – have experienced neurological problems.

        The extent and severity of these neurological issues has flown largely under the radar. Most people, including physicians, may not recognise neurological abnormalities for what they are when they appear – someone experiencing a seizure may simply look dazed, without any trembling or shaking. With its beeping machinery, sedative drugs and bed-bound isolation, an ICU environment can exacerbate and induce delirium, confounding our ability to link any symptom to the virus.

        Further complicating matters, many people suffering from the effects of Sars-CoV-2 are never actually tested for the virus, especially if they do not exhibit a cough or fever. It means that if they have neurological symptoms, we may never know if this was linked to Sars-CoV-2.

        “In fact, there is a significant percentage of Covid-19 patients whose only symptom is confusion” – they don't have a cough or fatigue, says Robert Stevens, associate professor of anaesthesiology and critical care medicine at Johns Hopkins Medicine in Baltimore, Maryland.

        “We are facing a secondary pandemic of neurological disease.”

        Much more in the link:
        • Early update.

        Coronavirus Cases: 9,206,609

        Deaths: 474,730

        Underreported US death count: 122,611

        Originally posted by Boon Mee View Post
        it's been blown way out of proportion.
        Keep your friends close and your enemies closer


          • EU may bar American travelers as it reopens borders, citing U.S. failures on virus

          European Union countries rushing to revive their economies and reopen their borders after months of coronavirus restrictions are prepared to block Americans from entering because the United States has failed to control the scourge, according to draft lists of acceptable travelers seen by The New York Times.

          That prospect, which would lump American visitors in with Russians and Brazilians as unwelcome, is a stinging blow to American prestige in the world and a repudiation of President Donald Trump’s handling of the virus in the United States, which has more than 2.3 million cases and upward of 120,000 deaths, more than any other country.

          European nations are currently haggling over two potential lists of acceptable visitors based on how countries are faring with the coronavirus pandemic. Both include China, as well as developing nations like Uganda, Cuba and Vietnam.

          Travelers from the United States and the rest of the world have been excluded from visiting the European Union — with few exceptions mostly for repatriations or “essential travel” — since mid-March. But a final decision on reopening the borders is expected early next week, before the bloc reopens July 1.

          A prohibition of Americans by Brussels partly reflects the shifting pattern of the pandemic. In March, when Europe was the epicenter, Trump infuriated European leaders when he banned citizens from most EU countries from traveling to the U.S. Trump justified the move as necessary to protect the United States, which at the time had roughly 1,100 coronavirus cases and 38 deaths.

          In late May and early June, Trump said Europe was “making progress” and hinted that some restrictions would be lifted soon, but nothing has happened since then. Today, Europe has largely curbed the outbreak, even as the United States, the worst afflicted, has seen more infection surges just in the past week.

          Prohibiting American travelers from entering the European Union would have significant economic, cultural and geopolitical ramifications. Millions of American tourists visit Europe every summer. Business travel is common, given the huge economic ties between the United States and the EU.

          The draft lists were shared with the Times by an official involved in the talks and confirmed by another official involved in the talks. Two additional EU officials confirmed the content of the lists as well the details of the negotiations to shape and finalize them. All of the officials gave the information on condition of anonymity because the issue is politically delicate.

          The forging of a common list of outsiders who can enter the bloc is part of an effort by the European Union to fully reopen internal borders among its 27 member states. Free travel and trade among members is a core principle of the bloc — one that has been badly disrupted during the pandemic.

          Some internal borders have practically remained closed while others have opened. Some member states that desperately need tourists have rushed ahead to accept non-EU visitors and pledged to test them on arrival. Others have tried to create closed travel zones between certain countries, called “bubbles” or “corridors.”

          Putting these safe lists together highlights the fraught, messy task of removing pandemic-related measures and unifying the bloc’s approach. But the imperatives of restoring the internal harmony of the EU and slowly opening up to the world are paramount, even if it threatens rifts with close allies including the United States, which appears bound to be excluded, at least initially.:
          • Today’s update

          Coronavirus Cases: 9,325,359

          Deaths: 478,530

          World population: 7,800,000,000 projection: 400,256,333 deaths

          Underreported US death count: 123,368

          Originally posted by Boon Mee View Post
          it's been blown way out of proportion.
          Keep your friends close and your enemies closer


            • COVID-19 study from University of Chicago examines distance virus travels through air

            In an effort to protect frontline healthcare workers, a study at the University of Chicago is trying to answer questions about how far the new coronavirus travels through the air.

            "The whole goal is to find out something about the disease process, how does this process interact with our body, how does it interact with the environment such that we can protest the people at the highest risk," said Dr. Jayant Pinto, University of Chicago Medicine.

            Researchers have set up small monitors on COVID-19 patients' rooms to measure viral material in hopes of learning about the distance those particles travel. The six-foot rule used in social distancing guidance is based on decades-old studies for other airborne diseases like tuberculosis.

            "We are going to do sampling at different distances so we can say, in the worst case scenario in the ICU, what distance can we find more virus in the air, what distance less in the air," Pinto explained.

            The study also measures how infectious the virus is as it travels through the air.

            "Is it the patients that are very sick early in the disease? Does that virus in the air go down with time or are there certain patients that put out more virus?" Pinto said.

            And does the virus in the air correlate with the amount of virus in a patient's nose or mouth? These are all questions Pinto and his team hope to answer and use on a widespread scale that could impact everything from social distancing guidelines to guidelines for workplaces and schools.

            Early results are expected by the end of July. By the time the study is complete, doctors hope to work with up to 20 patients.:
            • Early update.

            Coronavirus Cases: 9,373,807

            Deaths: 480,170

            Underreported US death count: 123,476

            Originally posted by Boon Mee View Post
            it's been blown way out of proportion.
            Keep your friends close and your enemies closer


              • Coronavirus deaths soar in Latin America and the Caribbean, with Brazil hit hardest

              Latin America and the Caribbean on Tuesday surpassed 100,000 coronavirus deaths, more than half of them in Brazil, according to an AFP count based on official figures.

              The pandemic is accelerating across the region, which now has a total of 2.1 million cases, with Brazil, Mexico, Peru and Chile the most affected countries.

              Brazil has the second-highest COVID-19 death toll in the world, after the United States, at more than 52,640 fatalities out of 1,145,906 confirmed cases.

              Alexandre Naime Barbosa, a medical professor at São Paulo State University, told the Reuters news agency last week that the true number of coronavirus cases in Brazil may actually be much higher, "because there is under-reporting of a magnitude of 5 to 10 times... The true number is probably at least 3 million and could even be as high as 10 million people."

              A federal judge ordered Brazilian President Jair Bolsonaro, who has famously compared the coronavirus to a "little flu," to wear a face mask in public, after the far-right leader repeatedly flouted containment measures in place in Brasilia.

              "The president has a constitutional obligation to follow the laws in force in the country, as well as to promote the general welfare of the people," the judge wrote.

              Mexico, also heavily hit by the virus, was struck Tuesday by a powerful 7.4 magnitude earthquake.

              The quake hit as the country of 127 million people recorded its highest number of coronavirus cases in a 24-hour period, with 6,288 new infections, according to the Ministry of Health.

              Peru, meanwhile, exceeded 260,000 coronavirus cases, as it marked 100 days under mandatory lockdown and received a donation of 250 ventilators from the United States.

              Its neighbor to the north, Colombia, extended its quarantine Tuesday until July 15, as its coronavirus cases continue to climb. The country has registered 2,404 deaths out of more than 73,500 cases.:
              • Today’s update.

              Coronavirus Cases: 9,455,054

              Deaths: 482,453

              World population: 7,800,000,000 projection: 398,002,317 deaths

              Underreported US death count: 124,147

              Originally posted by Boon Mee View Post
              it's been blown way out of proportion.
              Keep your friends close and your enemies closer


                • Coronavirus live news: cases worldwide growing by 1m per week with surge in the United States and Latin America

                As 1 million new cases of coronavirus are confirmed worldwide per week, the World Health Organization (WHO) has warned that hospitals are facing a shortage in oxygen concentrators needed to support the breathing of Covid-19 patients suffering from respiratory distress.

                “Many countries are now experiencing difficulties obtaining oxygen concentrators,” WHO director general Tedros Adhanom Ghebreyesus said. “Demand is currently outstripping supply.”

                The health agency has bought 14,000 oxygen concentrators from manufacturers and plans to send them to 120 countries in coming weeks, Tedros said. A further 170,000 concentrators – worth about US$100m – will be potentially available over the next six months.

                Cases worldwide passed 9.4 million on Thursday, with the WHO saying it expected global infections to pass 10 million by the end of the week. At least 480,000 people have died so far.:
                • Early update.

                Coronavirus Cases: 9,543,163

                Deaths: 485,294

                Underreported US death count: 124,282

                Originally posted by Boon Mee View Post
                it's been blown way out of proportion.
                Keep your friends close and your enemies closer


                  • Vaccine enters phase 3 trial

                  China reached an important new level of vaccine development with the start of the phase three clinical trial of an inactivated vaccine candidate against COVID-19 in the United Arab Emirates on Tuesday.

                  It is the first vaccine of its kind to reach a late-stage, mass-scale human trial, according to China National Biotec Group.

                  The Institute of Microbiology of the Chinese Academy of Sciences said in a statement on Tuesday that Chinese authorities approved the phase one trial of the nation's first recombinant protein vaccine against COVID-19 on Friday.

                  The recombinant protein vaccine is the nation's third type of vaccine, after an adenovirus vector vaccine and the inactivated vaccine, to enter clinical trials in China, the statement said.

                  The Wuhan and Beijing units of the CNBG each developed an inactivated vaccine candidate, and one or the other of these vaccine candidates were tested on a group of 2,240 people during phase one and two clinical trials, the CNBG said.

                  The Wuhan vaccine was found to be effective and safe, with no serious adverse effects, according to trial results published on June 16.

                  Various dosages and timings were tried. Those who received two doses at an interval of 28 days, all in the 18 to 59 age group, tested positive for neutralizing antibodies against the novel coronavirus.

                  The Beijing vaccine's test results will be published on June 28, the CNBG said on Tuesday. The UAE Ministry of Health and Prevention has approved the phase three trials, though it is unclear which vaccine will be used.

                  As for the recombinant protein vaccine, the Institute of Microbiology said in the statement that it has been shown to be safe and effective in animal tests and is easy to mass produce.

                  China's recombinant protein vaccine candidate has been jointly developed by the Institute of Microbiology and Anhui Zhifei Longcom Biopharmaceutical. The United States, Israel, Japan, Argentina, Thailand and other countries are working on similar recombinant vaccines, according to the World Health Organization.

                  Unlike an inactivated vaccine, which uses a whole dead targeted virus, and a vector vaccine, which uses a chemically weakened second virus as a carrier, a recombinant protein vaccine uses only part of the targeted virus to trigger a protective immune response.

                  This type of vaccine is known to provide very strong protection and is safe even for people who are immuno-compromised, the United States' National Institutes of Health said. Common recombinant vaccines include those against hepatitis B, influenza, whooping cough and human papillomavirus or HPV.

                  Some recombinant vaccines, however, require booster shots for ongoing protection. They also need added substances to enhance the immune response, the NIH said.

                  The novel coronavirus uses its spike protein to bind to ACE2 receptors on human cells and subsequently infect them. Therefore, scientists have chosen to focus on the spike protein as one of the major targets for vaccines and therapeutics.

                  The Institute of Microbiology said its recombinant protein vaccine has been tested on mice and rhesus monkeys and shown to produce highly potent virus neutralizing antibodies.

                  It also said the viral load in the test animals decreased noticeably, reducing the virus' damage to lung tissues. Moreover, the process used to manufacture the vaccine can be upgraded to industrial scale, resulting in high production output, low cost and relatively strong practicality.

                  However, the institute stressed that much work still has to be done in human trials before the vaccine could reach the market.

                  As of Monday, the WHO had recorded around 142 candidate vaccines in development around the globe, 13 of which have entered clinical trials. The AZD1222 vaccine candidate, created by researchers from the University of Oxford and biotech company AstraZeneca, entered concurrent phase two and three trials in the United Kingdom in late May.

                  In mid-June, US biotech company Moderna finalized its protocol for the phase three trial of its COVID-19 nucleic acid vaccine candidate mRNA-1273.

                  Chinese scientists and companies have tested six potential vaccines in clinical trials in China, including one vector, four inactivated and one recombinant protein vaccine.

                  Two Chinese vaccine developers, CanSino and Sinovac Biotech, have previously announced they plan to conduct phase three clinical trials of their products and related research in Canada and Brazil, respectively.:
                  • Today’s update.

                  Coronavirus Cases: 9,647,552

                  Deaths: 487,737

                  World population: 7,800,000,000 projection: 394,333,049 deaths

                  Underreported US death count: 124,570

                  Originally posted by Boon Mee View Post
                  it's been blown way out of proportion.
                  Keep your friends close and your enemies closer


                    • NokScoot Airlines to be liquidated

                    NokScoot Airlines’ board of directors decided to liquidate the low-cost airline, a statement from the airline said.

                    NokScoot’s shareholders will deliberate on the resolution and decide on the liquidator during an annual general meeting on July 14.NokScoot, a joint venture between Singapore Airline’s low-cost arm Scoot and Thailand-based airline Nok Air, has been unable to record a full-year’s profit since its inception in 2014. Much of this was contributed to the difficult in expanding its network in an intensely competitive environment, and unprecedented challenges arising from the Covid-19 pandemic have further exacerbated the situation.

                    Nok Airlines Plc on Friday also informed the Stock Exchange of Thailand the board’s resolution to terminate NokScoot Airlines.

                    According to the SET filing, NokScoot Airlines has been suffering continuous losses, which was worsened by the Covid-19 pandemic. The airline’s equity has been negative since 2019.:

                    Originally posted by Somchai Boonporn View Post
                    Perhaps a blessing in disguise for the Golden Land.
                    • New study finds troubling signs of "brain complications" in severe COVID-19 cases

                    A new coronavirus study out of the United Kingdom found troubling signs of brain complications in patients with severe COVID-19.

                    The study, published in The Lancet Psychiatry journal, looked at 153 patients who were hospitalized with severe cases of the disease, and found that 125 of them experienced a range of neurological and psychiatric complications that may be linked to the coronavirus.

                    "The patients survived, but they survived with residual effects of having had the nervous system affected by this virus," Dr. Bob Lahita told CBSN anchors Vladimir Duthiers and Anne-Marie Green on Friday.

                    The most commonly reported complication was stroke, occurring in 62% of the patients. Of the 77 reported stroke cases in the study, 57 were caused by a blood clot in the brain, nine were caused by a brain hemorrhage and one patient's stroke was caused by "inflammation in the blood vessels of the brain." The majority of the strokes occurred in patients age 60 or older.

                    About a third of patients in the study experienced "an altered mental state such as brain inflammation, psychosis and dementia-like symptoms," including signs of confusion or changes in behavior.

                    "Altered mental status is common in patients admitted to hospital with severe infection," the study notes, but adds that the researchers "observed a disproportionate number of neuropsychiatric presentations in younger patients."

                    Twenty-three of patients with an altered mental state were diagnosed with psychiatric conditions — the "vast majority" of which were found to be newly developed. However, researchers say it is possible some may have been simply undiagnosed before the patient developed the virus. Around half of that group were under 60 years of age.

                    "With regards to age, it is clear that people who are older are not going to do as well as people who are younger," Lahita said. But some younger people develop severe illness as well.

                    "We simply don't know who will be infected that will die," he said. "And we in the scientific community believe it has to do with immunogenetics — that means your inheritance of a certain kind of immune system which may make you susceptible to really doing badly once you're infected."

                    Researchers say the high proportion of younger patients diagnosed with these brain complications could be due to a higher chance of them being referred to a mental health specialist after showing signs of an altered mental state, while the same changes in older patients could have been more likely attributed to delirium and "not investigated further."

                    The University of Liverpool's Dr. Benedict Michael, one of the study's lead authors, called the study an "important early step" towards unraveling the link between neurological complications and COVID-19.

                    "We now need detailed studies to understand the possible biological mechanisms underlying these complications so that we can explore potential treatments," he wrote in a press release about the findings.:
                    • Today’s update.

                    Coronavirus Cases: 9,873,780

                    Deaths: 495,383

                    World population: 7,800,000,000 projection: 391,338,210 deaths

                    Underreported US death count: 127,328

                    Originally posted by Boon Mee View Post
                    it's been blown way out of proportion.
                    Keep your friends close and your enemies closer


                    • Should have added the graph below yesterday…..

                      Originally posted by Boon Mee View Post
                      it's been blown way out of proportion.
                      Keep your friends close and your enemies closer


                        • COVID-19 can stop the heart, and a defibrillator may not help, Penn study finds

                        Months into the COVID-19 pandemic, physicians still emphasize that key symptoms include a dry cough, fever, and shortness of breath — no surprise for a virus that infects the lungs.

                        Yet in the sickest patients, doctors keep finding collateral damage in the kidney, liver, and other organs.

                        A new Penn Medicine study suggests that in rare cases, the coronavirus can even stop the heart.

                        Among 700 COVID-19 patients at the Hospital of the University of Pennsylvania, nine suffered a sudden cardiac arrest after being admitted, the study authors reported recently. Seven of the nine were under age 60.

                        While doctors managed to resuscitate six of those nine, including five of the under-60 group, the findings are a reminder that COVID-19 can cause injury throughout the body, senior author Rajat Deo said.

                        The cardiac arrests were among 53 cases of abnormal heart rhythm identified by Deo and his co-authors. Most, including all nine of the arrests, occurred in patients treated in the intensive care unit.

                        Evidence suggests these heart malfunctions are not the result of the virus’ infecting heart cells, said Deo, a cardiac electrophysiologist and an associate professor at Penn’s Perelman School of Medicine. Instead, they appear to occur when the immune system overreacts to the virus, leading to dangerous inflammation.

                        “When the body is under so much stress, just general, overt systemic stress and inflammation, then at that time, they’re just predisposed to arrythmias,” Deo said.

                        Eight of the nine cardiac arrests were “nonshockable,” meaning they were not the type that can be restarted with a defibrillator.

                        “That means CPR and medication, and you pray that the pulse comes back,” Deo said.

                        Some of the heart malfunctions may be the result of abnormal blood clots that can occur in COVID-19 patients, he and his co-authors wrote in Heart Rhythm Journal.

                        Yet one of the abnormal heart rhythms they identified — atrial fibrillation, typically abbreviated as A-fib — can itself lead to clots, so it can be difficult to disentangle what caused what. It is possible that some patients suffer from thrombosis — clotting — as a direct result of COVID-19 and also as a result of the COVID-19-induced heart malfunction, Deo said.

                        “If you have COVID-19 and A-fib, it’s sort of like a double thrombotic disease,” he said. “It’s a double whammy.”

                        Many of the patients who experienced heart malfunction while hospitalized already suffered from diabetes, high blood pressure, and other underlying conditions known to be associated with severe consequences from COVID-19.

                        The abnormal heart rhythms in Penn’s patients are consistent with what physicians have reported elsewhere, said Chad M. Colon, a cardiology fellow at the University of Alabama at Birmingham Hospital.

                        As at Penn, the arrhythmias at UAB Hospital are occurring primarily in the intensive-care ward, he said.

                        Colon, who was not involved in the Penn study, agreed with the authors that the heart malfunctions are not the result of the virus’ infecting heart cells, but of the patients’ overall sickness.

                        “This is probably more just a manifestation of their critical illness,” he said. “These patients are just uniquely challenging.”

                        Deo said the next step is to keep following patients who experience the abnormal heart rhythms to see if they experience any long-term harm.

                        With the number of cases resurging in some parts of the country, they likely will have no shortage of people to study.:
                        • Today’s report.

                        Coronavirus Cases: 10,043,639

                        Deaths: 500,074

                        World population: 7,800,000,000 projection: 388,362,942 deaths

                        Underreported US death count: 128,074

                        Originally posted by Boon Mee View Post
                        it's been blown way out of proportion.
                        Keep your friends close and your enemies closer


                        • Horrific failure

                          Originally posted by Boon Mee View Post
                          it's been blown way out of proportion.

                          Keep your friends close and your enemies closer


                            • Some COVID-19 patients aren't getting better. Major medical centers are trying to figure out how to help.

                            "What we need is more research to explain where the symptoms are coming from," one expert said.

                            Major medical centers nationwide trying to understand why some COVID-19 patients continue to have symptoms weeks and even months after having been diagnosed with the coronavirus.

                            Amy Watson, 47, is one of those patients. She's had a fever, she said, for more than 100 days.

                            "It's been maddening," said Watson, a preschool teacher in Portland, Oregon. Since mid-March, her temperature has crept up to 100 or 101 degrees almost daily by midafternoon.

                            She was diagnosed with COVID-19 in April, about a month after her symptoms — cough, congestion and extreme fatigue — began. Now, those symptoms have evolved into weeks of low-grade fever and a burning sensation under her skin.

                            Watson's illness was never severe enough to warrant hospitalization. Instead, her symptoms have lurked in the background, never fully resolving. Doctors have had few answers for her.

                            "Physicians should not be discounting the experience of individuals, especially in the case of a disease that we know next to nothing about," said David Putrino, a physical therapist and assistant professor at the Mount Sinai Health System in New York City.

                            "This is very real condition," he said.

                            Last week, the World Health Organization and the Centers for Disease Control and Prevention also acknowledged such reports and said they are working to better understand the recovery phase of the illness.

                            Physicians should not be discounting the experience of individuals, especially in the case of a disease that we know next to nothing about.

                            Putrino and colleagues at Mount Sinai have begun monitoring COVID-19 patients who experience a milder, long-lasting form of the virus at home.

                            "What we're trying to understand is what does this new syndrome look like?" Putrino said. "How might we manage it, and how might we help some of these people get back to a regular daily life?"

                            Dr. Jessica Dine, a lung doctor at Penn Medicine in Philadelphia, said she began noticing a subset of COVID-19 patients whose symptoms lingered long after their diagnoses thanks to a hospital program called COVID Watch, a texting service that does daily check-ins with COVID-19 patients at home.

                            Now Dine, who is also the director of the advance consultative pulmonary division at Penn Medicine, is working with those patients to better understand their illness.

                            Her team starts by ruling out obvious causes of the long-term symptoms.

                            "The first thing I do is make sure is there not something new going on, that we're not missing something," Dine said, such as a secondary infection, a complication of the virus or a side effect of treatment.

                            If Dine and her team are able to rule out other causes, they have two hypotheses for what's going on. The first is that it's possible that the virus is still somewhere in the body, undetectable through testing. The other is that the virus is gone from the body but patients are experiencing what's referred to as post-viral inflammatory syndrome, in which the body's immune system remains "revved up" even after the virus goes away.

                            "What we need is more research to explain where the symptoms are coming from," Dine said.

                            One theory is that the inflammation triggered by COVID-19 damages the autonomic nervous system, which affects functions we don't consciously think about, such as digestion, sweating, sleep, heart rate and blood pressure.

                            Dr. Mitchell Miglis, a neurologist at Stanford University, ascribes to this theory. He said it appears that for some people, "the body is still damaged" even when the virus is long gone.

                            "It can take a really long time to fully recover," he said, adding that it's too soon to know whether the condition will clear up eventually or whether the symptoms will continue as a chronic disease.

                            Miglis and his team at Stanford have begun developing a registry to track such long-term COVID-19 patients over time.

                            There is no specific therapy for the kind of long-term inflammation doctors suspect may be causing problems, other than medications to ease symptoms such as cough or fever. And Dine said there is no good treatment for one of the most debilitating manifestations of COVID-19: extreme fatigue.

                            Putrino, of Mount Sinai, has begun to develop a kind of protocol for people whose symptoms, like Watson's, have lingered for weeks and weeks.

                            Plans are individualized, but they usually involve very specific ways of training the body to compensate for unconscious functions. Many patients are given exercise plans, sleep regimens and nutrition guidelines.

                            Mount Sinai dietitian Adena Neglia is working with Putrino on the nutrition aspect of the protocol. "During times of stress and anxiety, some people may turn to food, while others turn away from food," Neglia said, adding that nourishment is important to support a healthy immune system.

                            Experts elsewhere echo the guidance to focus on behaviors that will keep people as healthy as possible. "Eat right and stay hydrated, especially during this time with increasing summer heat," said Dr. Gary LeRoy, president of the American Academy of Family Physicians.

                            LeRoy, a practicing physician at the East Dayton Health Clinic in Dayton, Ohio, said he hasn't treated any COVID-19 patients with long-term symptoms. But he has counseled some who said they struggled with lingering fatigue about ways to get their energy back.

                            Watson has found bits of relief from her symptoms with rest, "which is hard, because I'm a go-go-go kind of person," she said.

                            She wants other COVID-19 patients with lingering symptoms to know they're not alone.

                            "You're not crazy. These symptoms are real," Watson said. "If you find a medical professional is not listening to you, find a different one.":
                            • Underreported US death count: 128,211

                            Originally posted by Boon Mee View Post
                            it's been blown way out of proportion.
                            Keep your friends close and your enemies closer


                              • UW study: 75% of US workers can’t work exclusively from home, face greater risks during COVID-19 pandemic

                              The study by University of Washington found that the majority of U.S. workers are in jobs that cannot be done from home during a pandemic, leaving them vulnerable.

                              The University of Washington has released a study showing about 75% of U.S. workers, or 108 million people, are in jobs that cannot be done from home during a pandemic, putting them at increased risk for exposure to COVID-19.

                              The majority of those workers are also at higher risk for other job disruptions such as layoffs, furloughs or reduced hours, and they represent some of the lowest-paid workers in the workforce, according to Marissa Baker, an assistant professor in the UW Department of Environmental & Occupational Health Sciences and the author of the study.

                              “This pandemic has really exacerbated existing vulnerabilities in American society, with workers most affected by the pandemic and stay-at-home orders being significantly lower-paid and now also at increased risk for mental health outcomes associated with job insecurity and displacement, in addition to increased risk of exposure to COVID-19 if they keep going to work,” said Baker.

                              The remaining 25% of U.S. workers, or 35.6 million people, are in jobs that can be done at home. Those jobs are usually in highly-paid occupational sectors such as finance, administration, computer, engineering and technology, said the study. As the economy begins to reopen, Baker said these workers will continue to be better protected from exposure to COVID-19 and disruptions to their jobs.

                              “The most privileged workers will have a job that can be done at home, reducing their risk of exposure, and enabling them to continue to work even as office buildings were closed. Unfortunately, only a quarter of the U.S. workforce falls into this category. The fact that these are some of the highest-paid workers in the U.S. is no surprise,” Baker added.

                              Those workers will also have an increased ability to care for a child at home, which continues to grow the disparity between the top quarter of the workforce and the rest, the study found.

                              The study was published on June 18 in the American Journal of Public Health.:
                              • Yesterday’s update.

                              Coronavirus Cases: 10,196,218

                              Deaths: 503,146

                              World population: 7,800,000,000 projection: 384,901,421 deaths

                              Underreported US death rate: 128,389

                              Originally posted by Boon Mee View Post
                              it's been blown way out of proportion.
                              Keep your friends close and your enemies closer


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