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How Covid-19 Might Spread to You

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  • Oh dear, looks like the crash diet has staved off heart failure for the time being and he can continue licking the narcissist's tiny balls.....


    • Originally posted by Cujo View Post

      Yes Smeg is being an annoying off topic ass but for the most part he's just being ignored. (which triggers him even more unfortunately)
      Indeed. His stated reason for being here is to attack other posters and he drags threads down with all his off-topic sneering and compulsive shit-flinging.

      People should just ignore him. Frankly it's amazing how some posters willingly submit to him and allow themselves to be dragged down in his vortex.


      • Waaaaaambulance to patient suffering from Pretend-Ignore Syndrome at office of shitty Chiang Mai metal factory on the double please!


        • GOP'ers fudging numbers to justify reopening. These people care more for money than human lives (with the exception of their own obviously):

          Republicans lie, people die.


          • Originally posted by Arthur Daley View Post
            He can't contain his Trump-sneering to the Trump-sneering thread. He's not getting enough attention there....
            With nobody reading Soapbox anymore due to the 2 main contributors being total frauds Ergenbergen has to gatecrash any thread he can to get his attention seeking fix. He's like an infant
            Last edited by Mr Tinkles; 05-21-2020, 03:36 PM.


            • Thread: How Covid-19 Might Spread to You
              Originally posted by Mr Tinkles View Post

              Bold argument to be making that you don't read a forum because of someone and they're attention seeking when you make practically every thread about them.

              Maybe they don't read Soapbox because you were trying to impress me with stories of buying a house in the Trump thread Mrs. Tinkles.

              Last edited by Ergenburgensmurgen; 05-21-2020, 04:20 PM.


              • ^The fruit picker is upset because the last couple cartoon posts it added in the soapbox were deleted.

                Keep your friends close and your enemies closer


                • Originally posted by S Landreth View Post
                  ^The fruit picker is upset because the last couple cartoon posts it added in the soapbox were deleted.

                  Figures, it never quite posts the truth.


                    • Moderna partner brings production muscle to covid battle

                    Drugmakers racing to make covid-19 vaccines and therapies are seeking out specialized manufacturers like Moderna's partner Lonza Group that can scale up production to billions of doses needed to supply the world.

                    After the first batches of Moderna's vaccine are produced in the U.S. in July, Lonza expects to produce initial "commercial volumes" at a site in Portsmouth, New Hampshire, in December, followed by a location in Visp, Switzerland, in February, Chairman Albert Baehny said in an interview. Each line could make as many as 100 million doses per year.

                    Companies and countries are rushing to secure manufacturing muscle for weapons against Covid-19 as the worldwide death toll climbs past 320,000 and the clamor for any kind of therapy surges. Innovative biotechnology companies like Moderna lack the size and experience to produce in bulk, and Lonza has been contacted by scores of other developers that need its services.

                    "We've had more than 100 inquiries, maybe 120, 140, I don't know," Baehny said. While Lonza has agreed with Moderna to make as many as 1 billion doses a year, Baehny said the company still can take on more production and expects to reach a few more collaboration pacts.

                    The severity of the pandemic is spurring companies to move quickly. Vaccines are seen as the key to ending lockdowns and restarting economies, while therapies could play a key role until those inoculations arrive. Many companies are moving to boost production capacity and know-how months before their products are fully tested, so they can hit the market at full throttle.

                    Making enough shots to quickly meet global necessity, "even if it has a relatively simple manufacturing process, should not be underestimated," analysts at Jefferies wrote in a report earlier this month. "We believe large-scale vaccine manufacturing may present one of the biggest challenges and potential bottlenecks in the Covid-19 vaccine quest."

                    Pent-up demand can be seen as patients snap up coronavirus treatments, proven or not. Some people with rheumatoid arthritis and lupus who depend on hydroxychloroquine were unable to find the drugs after President Donald Trump touted it for Covid-19.

                    Meanwhile, Gilead Sciences is working to produce more than 140,000 doses of remdesivir by the end of May and exceed 1 million by the end of the year. The drug received emergency use authorization from the U.S. Food and Drug Administration after it reduced covid-19 patients' recovery time in a clinical trial.

                    Drugmakers around the world are stitching together production plans, undeterred by questions raised by some of their early results. Moderna, whose stock had quadrupled since the beginning of the year, tumbled 10% Tuesday after a report on the Stat website that the company hadn't produced data critical to assessing its vaccine. Shares of the U.S. company declined as much as 5.9% Wednesday, while Lonza gained as much as 2.4%.

                    A fast-moving University of Oxford vaccine group has also faced doubts from some scientists. Manufacturing partner AstraZeneca still plans to make 100 million doses of the experimental inoculation by the end of the year. Johnson & Johnson last month announced a collaboration with Emergent BioSolutions, the first in a series of deals the U.S. pharma giant expects as it pursues a goal of supplying more than 1 billion doses globally. J&J reached another manufacturing pact with Catalent.

                    With the Moderna deal sealed, Basel-based Lonza is focusing now on partnerships with developers of Covid therapies, but it may also join with another vaccine maker, Baehny said. That's assuming the company or institution uses a different technology from the approach Moderna is taking, relying on genetic material called mRNA, he added.

                    "There are limits to what we can really offer," he said. "It's why we are and we will stay very focused."

                    Lonza is producing the active ingredients of the vaccines, not the final product, he said. If needed, the company can add another manufacturing line in North America, two more in Switzerland and one in Singapore. Each line will cost about $60 million to $70 million, though the first in the U.S. will be funded by the government, Baehny said.

                    "We are investing in manufacturing without knowing if basically the vaccine will be accepted by the FDA," he said. That's "a risk we never took in the past.":
                    • Early report

                    Coronavirus Cases: 5,124,962

                    Deaths: 330,803

                    under reported US death count: 95,021

                    Originally posted by Boon Mee View Post
                    it's been blown way out of proportion.
                    Keep your friends close and your enemies closer


                    • Originally posted by Somchai Boonporn View Post

                      Perhaps a blessing in disguise for the Golden Land.

                      Dont get sick of me just yet, for I will be here for quite a while


                        • Thailand - State of emergency could be extended for another month

                        The National Security Council (NSC) will again ask the Centre for Covid-19 Situation Administration to extend the state of emergency for another month until June 30.

                        The state of emergency was last month extended to May 31, after a similar request from the NSC.NSC secretary-general Gen Somsak Rungsita said on Thursday (May 21) that it will also ask the centre and the Cabinet to consider the third phase of lockdown relaxation and the curfew reduction.

                        He said citizens had cooperated well with the first and second phases of relaxation, as shown by the falling infection rate and widespread practise of preventive measures. However, the office is concerned about new Covid-19 cases arriving from foreign countries, and says measures must be found to deal with international travel when it restarts.

                        Somsak added that the emergency decree helped the prime minister run the country during the pandemic and was not a political tool, as some claimed.:

                        Originally posted by Somchai Boonporn View Post
                        Perhaps a blessing in disguise for the Golden Land.
                        • At Brazil's biggest cemetery, grave diggers take own measure of coronavirus toll

                        SAO PAULO (Reuters) - As Oswaldo dos Santos watched several men in protective suits dig a hasty grave for his 36-year-old son, his grief was mixed with fear: What if he had the coronavirus? What if they all did?

                        Dos Santos lived with his son until Sunday, when he was suddenly hospitalized with severe respiratory problems. Like so many now filling the graves in Brazil’s biggest cemetery, the son died before getting the results of a coronavirus test.

                        “I think he had the disease,” Dos Santos told Reuters from among more than 1.5 million graves in Vila Formosa, on the outskirts of Sao Paulo, where freshly dug rows are filled with the bodies of those infected - knowingly or not - by the virus.

                        The burial took 10 minutes, under new guidelines to limit crowds and contagion.

                        The grave diggers of Vila Formosa are working at a grueling pace, as their load has doubled to almost 60 burials per day. Workers are convinced the coronavirus is quietly killing far more than official statistics show.

                        “That row of graves was meant to last three months, but it only lasted one,” one worker said, pointing at a section covered in freshly topped soil.

                        Five grave diggers told Reuters that the number of burials has swelled with the ranks of those who died before getting the results for coronavirus tests. Those cases are not immediately counted in Brazil’s official statistics, which on Thursday rose to almost 300 dead and 7,910 confirmed cases, by far the most in Latin America.

                        “The numbers in the newspapers are very wrong,” said one grave digger. “The real number is twice as high, maybe triple.”

                        Brazil’s health minister, Luiz Henrique Mandetta, acknowledged on Wednesday that coronavirus cases are likely underreported due to delays in testing.:
                        • Moderna CEO says coronavirus vaccine could be ready by end of year

                        The CEO of Moderna, one of the biotech companies working to develop a coronavirus vaccine, said on Wednesday that one could be ready to be sent to the Food and Drug Administration (FDA) by the end of this year.

                        “It is possible — assuming a best-case scenario and there are many risks that could derail us, obviously — but we could potentially be in a position to file to the FDA toward the end of the year or early next year,” Stéphane Bancel said on Fox Business's “Mornings with Maria."

                        “Again, it's a best-case scenario,” he emphasized.

                        Moderna announced this week that early data from a phase one clinical trial showed that people given a potential vaccine generated an immune response similar to one in people who had recovered from the disease. Additionally, company's potential vaccine was successful in preventing the virus from replicating in mice’s lungs in another study, it said.

                        The company, which is working with the National Institute of Allergy and Infectious Diseases, led by Anthony Fauci, will soon begin a phase two trial and said it hopes to begin a phase three trial in July.

                        Bancel has said that manufacturing of the vaccine could start as early as July, even before trials are complete, through a partnership with the Swiss biotech company Lonza.

                        "They are allowing us through their infrastructure and their factories to potentially build manufacturing capacity to deliver up to 1 million doses," he said on Wednesday.:
                        • Today's update.

                        Coronavirus Cases: 5,174,533

                        Deaths: 333,185

                        World population: 7,800,000,000 projection: 502,237,206 deaths

                        underreported US death count: 96,206
                        • U.S. Could Have Saved 36,000 Lives If Social Distancing Started 1 Week Earlier: Study

                        The U.S. could have prevented roughly 36,000 deaths from COVID-19 if broad social distancing measures had been put in place just one week earlier in March, according to an analysis from Columbia University.

                        Underlining the importance of aggressively responding to the coronavirus, the study found the U.S. could have avoided at least 700,000 fewer infections if actions that began on March 15 had actually started on March 8.

                        The U.S. currently has more than 1.5 million confirmed COVID-19 cases, and more than 93,000 people have died from the disease, according to data compiled by Johns Hopkins University.

                        In the analysis, researchers applied transmission models to data drawn from the pandemic's actual course county by county in the U.S. — the worst-hit nation in the world. The main focus of the study was the period from March 15 to May 3, when U.S. states and counties implemented "measures enforcing social distancing and restricting individual contact."

                        And if restrictions had gone into effect in the U.S. two weeks earlier, researchers found, nearly 54,000 people would still be alive and nearly a million COVID-19 cases would have been avoided.

                        The World Health Organization declared COVID-19 a global pandemic on March 11 — an act that had been widely anticipated. Two days later, President Trump declared a national emergency in the U.S. But it took even longer for dozens of U.S. states to order social distancing and shut down business as usual.

                        March 15 is the day the Centers for Disease Control and Prevention advised against gatherings of 50 or more people for the next two months. But the federal agency also said the guidance didn't apply to schools or businesses. That same day, the governors of Washington state and Illinois – two of the first U.S. hot spots — ordered all bars and restaurants to close. Other cities and states were also moving to shut down social life, and by Monday, March 16, many schools began to close.

                        If the U.S. had been able to follow social distancing restrictions to the same degree on March 8, the study says, it would have sharply cut the respiratory disease's impact — and the early action would have made a big difference in densely populated and hard-hit areas such as New York City.

                        The paper says that if restrictions had taken effect on March 8, the New York metropolitan area would have had at least 209,987 fewer cases and 17,514 fewer deaths.

                        The study was funded in part by the National Institutes of Health, the National Science Foundation and the Morris-Singer Foundation. The researchers' findings are in "pre-print" status, meaning their article hasn't been certified by peer review.

                        The new analysis finds social distancing has been effective in slowing the spread of the virus, and it looks at what might happen if states or local governments lift those orders too soon — or wait too long to reimpose them.

                        The researchers say that once counties and states reopen their economies and lift restrictions, the number of daily confirmed cases will likely continue to decline for almost two weeks. That residual benefit from the shutdown, paired with the lag time between COVID-19 infection and diagnostic confirmation, creates "a false signal that the pandemic is well under control," they write.

                        Citing a persistent vulnerability to the virus, the researchers say their models describe "a large resurgence of both cases and deaths ... peaking in early- and mid-June," even if restrictions are reimposed, just two or three weeks after being relaxed.

                        "We have to be so responsive and so attentive to what's going on," researcher Jeffrey Shaman tells NPR, "and able to quickly identify when there's a resurgence of the infection in the community and to respond to it quickly and to have the will to do so and not repeat our mistakes."

                        As of Wednesday, all 50 states have at least partially eased restrictions on businesses, with a mix of policies letting restaurants or stores welcome customers. Many states still have stay-at-home orders or other social distancing policies in effect, and some cities and counties are maintaining shutdown orders.: -

                        Originally posted by Boon Mee View Post
                        it's been blown way out of proportion.
                        Keep your friends close and your enemies closer


                          • CCSA approves extension of emergency for a month

                          The Centre for Covid-19 Situation Administration (CCSA) meeting approved on Friday (May 22) extension of the state of emergency for a month until June 30, as proposed by the National Security Council (NSC).

                          The NSC on Thursday (May 21) decided to propose the emergency matter as well as those related to the next phase of relaxation of the lockdown and curfew to the CCSA. It invited representatives from related agencies like national security, public health and economy to hold a meeting in order to discuss the state of emergency, which has been enforced since March 26.

                          After approval by the CCSA, the NSC will propose this matter again to the Cabinet next Tuesday.:

                          Originally posted by Somchai Boonporn View Post
                          Perhaps a blessing in disguise for the Golden Land.
                          • Early report.

                          Coronavirus Cases: 5,198,686

                          Deaths: 334,694

                          Underreported US death count: 96,359

                          Originally posted by Boon Mee View Post
                          it's been blown way out of proportion.
                          Keep your friends close and your enemies closer


                          • Comment

                              • Another large study finds no benefit to hydroxychloroquine for COVID-19/The medication may, in fact, lead to an increased risk of death.

                              Hydroxychloroquine does not help COVID-19 patients, and indeed may increase deaths, according to a large, international study published Friday in The Lancet.

                              The research is the latest to show the drug — which President Donald Trump this week said he was taking as a preventive strategy — can lead to potentially deadly heart problems.

                              Hydroxychloroquine is an antimalarial drug that's also used to treat lupus and rheumatoid arthritis. There is no evidence it can help prevent the coronavirus, though such studies are ongoing.

                              The new study, led by investigators at Brigham and Women's Hospital Center in Boston, included data from 671 hospitals on six continents.

                              Researchers compared the outcomes of nearly 15,000 COVID-19 patients received the drug or a similar compound, chloroquine, plus an antibiotic with those of about 81,000 COVID-19 patients who had not received the drugs. It was an observational study, meaning patients were not randomized to get a particular drug or a placebo.

                              "We were unable to confirm a benefit of hydroxychloroquine or chloroquine, when used alone or with" an antibiotic, the study authors wrote. What's more, the patients who got the drugs were more likely than the others to die in the hospital.

                              Hydroxychloroquine was also linked to abnormal heart rhythms. That side effect is also possible among people who are already on the drug for other, approved uses. However, those patients are generally carefully monitored.

                              The study authors called for high-quality, randomized clinical trials to confirm any harms or benefits of the medication.

                              "In the meantime, we suggest these drugs should not be used as treatments for COVID-19 outside of clinical trials," Dr. Mandeep Mehra, lead author of the study and the executive director of the Brigham and Women's Hospital Center for Advanced Heart Disease in Boston, said in a statement.:
                              • Today’s update.

                              Coronavirus Cases: 5,281,143

                              Deaths: 338,716

                              World population: 7,800,000,000 projection: 500,267,612 deaths

                              Underreported US death count: 97,528

                              Originally posted by Boon Mee View Post
                              it's been blown way out of proportion.
                              Keep your friends close and your enemies closer


                                • Thai Sex workers left in cold by outbreak/Up to 200,000 made jobless by Covid-19

                                Thousands of sex workers have been denied access to relief cash amid the coronavirus outbreak despite their contribution to the once-thriving tourism industry, a forum was told.

                                Suparnee Pongruengphant, the project manager for Gender Equality and Social Inclusion at the United Nations Development Programme, said an agency survey has shown that up to 200,000 sex workers in Thailand suddenly lost their jobs when the government ordered the closure of nightlife venues in late March to curb the spread of Covid-19.

                                "It is sad to say that the government is not doing enough to support this group of people and their immediate needs. They are denied support because they are not categorised as [formal] labourers and legalised in Thailand. … [They should be] entitled to the same protections and welfare services as other professions," she told the online forum on Thursday.

                                The event, "Helping Thailand's most vulnerable: Sex workers & Covid-19, the fallout", was held by the Foreign Correspondents' Club of Thailand.

                                Ms Suparnee said sex workers are marginalised because many of them do not have access to education or opportunities to seek employment in the formal sector, forcing them into the sex trade. It is even more difficult for migrant and transgender prostitutes to seek community support.

                                On May 19, CCSA spokesman Taweesilp Visanuyothin said the government will reopen nightlife venues, with adjustments, if the number of new daily cases stays in single digits for the foreseeable future. But Ms Suparnee said when business resumes, sex workers will be put at risk of infection because a vaccine is still unavailable and the nature of their work requires close contact with clients.

                                "The fact that many of them don't have enough savings to cover health and medical costs makes the situation even worse for them," she said.

                                Assoc Prof Chalidaporn Songsamphan, a political science lecturer at Thammasat University and president of the Service Workers In Group Foundation, said many sex workers cannot gain access to state assistance because prostitution has been "an elephant in the room" despite their contribution to the tourism industry.

                                "We surveyed female sex workers in Bangkok who applied for the 5,000-baht monthly cash handout. Those who outed themselves didn't get any support. There is no place for sex workers. … I don't think this government will even think about the existence of the sex industry," she said.: - -

                                Originally posted by Somchai Boonporn View Post
                                Perhaps a blessing in disguise for the Golden Land.
                                • Early update.

                                Coronavirus Cases: 5,326,230

                                Deaths: 340,383

                                Underreported US death count: 97,655

                                Originally posted by Boon Mee View Post
                                it's been blown way out of proportion.
                                Keep your friends close and your enemies closer